76ers Vs. Celtics Prediction, Odds And Best Nba Prop Bets For Wednesday, Oct. 22

The Boston Celtics unfastened up their 2025-26 play pinch a location matchup against nan Philadelphia 76ers connected Wednesday night.

Both teams will commencement nan play without cardinal pieces arsenic Jayson Tatum hopes to play sometime this play aft suffering an Achilles injury, and Jared McCain is slated to miss a fewer weeks pinch a thumb injury. The Sixers will besides beryllium without Paul George owed to a knee injury.

The oddsmakers person nan Celtics arsenic flimsy location favorites against nan Sixers. 

Which Atlantic Division rival will get a triumph successful their opener?

Let’s return a look astatine nan odds, players to watch and my prediction for Wednesday night’s matchup.

Odds via DraftKings Sportsbook

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Moneyline

Total

76ers vs. Celtics How to Watch

76ers Injury Report

Celtics Injury Report

76ers vs. Celtics Best NBA Prop Bets

Celtics Best NBA Prop Bet

Jaylen Brown has go a unit successful Boston, and he’s going to person to enarthrosis much of nan load this play without Jayson Tatum. There are still immoderate pieces astir him, but nan seasoned will beryllium starring nan way.

Brown averaged 5.8 rebounds per crippled past season, which is simply a tad higher than his profession mean of 5.3. However, he vanished nan play peculiarly beardown connected nan solid pinch astatine slightest six rebounds successful each of his last 10 games (including nan playoffs).

Overall, Brown had complete 5.5 rebounds successful 59% of his games past season, including each 3 meetings against nan Sixers. In fact, he had 23 rebounds successful 3 games against Philadelphia pinch 7, 10, and 6 boards.

The 76ers tin beryllium a vulnerable squad whenever Joel Embiid is patient and connected nan court, and nan large man appears to beryllium fresh to spell for nan play opener. 

The Celtics whitethorn person won nan last 3 meetings past season, but nan Sixers won nan first matchup 118-114 successful Boston past December.

Boston fizzled retired successful nan playoffs without Tatum, and I’m happy to slice them to statesman nan play until we spot really these new-look Celtics perform.

Pick: 76ers (+120)

Odds refresh periodically and are taxable to change.

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